Intracytoplasmic sperm injection (ICSI)​

Intracytoplasmic sperm injection Guide in Turkey

intrasytoplasmic sperm injection

Introduction

Intracytoplasmic sperm injection (ICSI) is a revolutionary technique in the world of assisted reproductive technology, particularly in the context of in vitro fertilization (IVF). We’ll delve into the intricacies of the ICSI process, its benefits, and what individuals can expect during treatment.

intrasytoplasmic sperm injection surgery

Overview

Intracytoplasmic sperm injection (ICSI) is a specialized form of in vitro fertilization (IVF) used primarily to treat male infertility. During this procedure, a single sperm is directly injected into the cytoplasm of an egg, enhancing the chances of fertilization. ICSI is particularly beneficial for couples struggling with low sperm count, poor sperm motility, or abnormal sperm morphology.

benefits of intracytoplasmic sperm injection

There are several benefits of intracytoplasmic sperm injection procedure, which we will mention some of them:

• Overcomes male infertility issues:

ICSI can be beneficial for men with a low sperm count or poor sperm motility.

• High success rate:

The targeted approach of ICSI often leads to higher rates of fertilization compared to traditional IVF methods.

• Suitable for various fertility conditions:

ICSI can be a solution for couples with unexplained fertility struggles.

• Reduced need for sperm samples:

Fertility specialists can retrieve sperm directly from the testes, eliminating the need for multiple samples.

• Enables use of frozen sperm:

ICSI allows for the successful fertilization of eggs using frozen sperm, offering more options for couples.

 

 

prepare for intracytoplasmic sperm injection

When you’re getting ready for intracytoplasmic sperm injection, there are a few important steps to follow. First, you’ll need to undergo fertility assessments to evaluate both egg and sperm quality. 

Next, hormonal stimulation will typically be prescribed to encourage the ovaries to produce multiple eggs. It’s essential to attend all monitoring appointments during this process. Also, make sure to discuss any medications you’re taking with your doctor.

steps of intracytoplasmic sperm injection procedure

The steps of intracttoplasmic sperm injection procedure are as follow:

Step 1- Ovarian stimulation:

The female partner undergoes ovarian stimulation with hormones. This is done to produce multiple eggs for retrieval.

Step 2- Monitoring follicle development:

Regular ultrasound scans and blood tests are conducted, and the development of the follicles is monitored to ensure optimal egg maturation.

Step 3- Egg retrieval:

When the follicles are mature, a trigger injection is given. Approximately 36 hours later, a minor surgical procedure is performed to retrieve the eggs from the ovaries.

Step 4- Sperm collection:

A sperm sample is collected from the male partner through ejaculation. If necessary, sperm can also be retrieved surgically from the testis.

Step 5- Sperm preparation:

The sperm sample is processed in the laboratory, then healthy and motile sperm are selected for injection.

Step 6- Injection process:

Under a microscope, a single sperm is drawn into a tiny glass needle, then the selected sperm is injected directly into the cytoplasm of each mature egg.

Step 7- Fertilization observation:

The eggs are closely monitored for signs of fertilization. This usually occurs within 16-20 hours post-injection.

Step 8- Fertilized eggs (embryos) are cultured in the lab for several days. Embryologists assess the quality of the developing embryos.

Step 9- Embryo transfer:

One or more healthy embryos are selected for transfer. This procedure is performed through a thin catheter inserted into the uterus.

Step 10- Luteal phase support:

About 10-14 days post-transfer, a pregnancy test is conducted. This determines if the procedure was successful.

recovery after intracytoplasmic sperm injection procedure

After intracytoplasmic sperm injection, you may experience mild discomfort, such as cramping or bloating, but this should subside within a few days. It’s important to take it easy for a few days after the procedure. You have to drink plenty of fluids to stay hydrated. Over-the-counter pain relievers can help manage any discomfort. Attend any scheduled follow-up appointments to monitor progress.

risks and complications of intrasytoplasmic sperm injection

The risks and complications of intracytoplasmic sperm injection procedure are as follow:

• Ovarian hyperstimulation syndrome (OHSS):

OHSS is a condition that can occur when ovaries are stimulated excessively.

• Multiple pregnancies:

There is a higher likelihood of twins or triplets due to embryo transfer.

• Sperm extraction risks:

Sometimes, sperm must be retrieved from the testicles or epididymis. This procedure may cause pain, swelling, hematomas, or infection at the extraction site.

• Anesthesia risks:

ICSI procedures may require anesthesia. Anesthesia risks include reactions to anesthesia, including respiratory issues or allergic reactions.

• Genetic risks:

The sperm used in ICSI may carry genetic abnormalities, which increases the risk of certain genetic disorders in the offspring.

 

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ICSI is a specialized form of in vitro fertilization (IVF).It involves the direct injection of a single sperm into an egg.This technique is primarily used for male fertility issues, such as low sperm count or poor sperm motility.

Ovarian Stimulation: The female partner undergoes hormonal treatment to stimulate the ovaries to produce multiple eggs.
Egg Retrieval: Once the eggs are mature, a minor surgical procedure is performed to retrieve them.
Sperm Collection: Sperm is collected from the male partner or a sperm donor.
Injection Process: A single sperm is selected and injected directly into an egg using a fine needle.
Fertilization and Culture: The injected eggs are monitored for fertilization and subsequently cultured for embryo development.

ICSI is recommended for:

Men with low sperm count.
Men with poor sperm motility.
Cases of previous unsuccessful IVF cycles.
Couples with genetic concerns requiring sperm selection.

Success rates vary depending on several factors, including:

Age of the female partner.
Quality of the eggs and sperm.
Overall health and fertility history.
Typically, younger women tend to have higher success rates.

While ICSI is generally safe, potential risks include:

Ovarian hyperstimulation syndrome (OHSS) due to hormonal therapy.
Multiple pregnancies if more than one embryo is implanted.
Genetic abnormalities, especially in cases of severe male factor infertility.

Results

Intracytoplasmic sperm injection is an advanced form of assisted reproductive technology. Typically used during in vitro fertilization (IVF), ICSI allows for better control over fertilization, especially in cases of low sperm count or poor sperm motility.

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